洋薊(朝鮮薊)選擇不同語言的俗名 & 名稱

洋薊(朝鮮薊)選擇不同語言的俗名 & 名稱

朝鮮薊，食用薊，花園朝鮮薊，全球朝鮮薊
Globe artichoke, French artichoke

義大利 Carcioffa, carciofa, carciofo,
法文 Artichaut, Artichaut commun,
德文 Artischocke,
西班牙 Alcachofa,
葡萄牙 Alcachofra,
索馬利文 Kharshoul, Kharsuf

2013 朝鮮薊花苞的化學成分和潛在的抗潰瘍能力

2013朝鮮薊花苞的化學成分和潛在的抗潰瘍能力

Chemical constituents and anti-ulcerogenic potential of the scales of Cynara scolymus (artichoke) heads

Mahmoud I Nassar, Tahia K Mohamed, Abdelsamed I Elshamy, Sayed A El-Toumy, Azza M Abdel Lateef and Abdel-Razik H Farragd

DOI 10.1002/jsfa.6065

c 2013 Society of Chemical Industry

http://www.ncbi.nlm.nih.gov/pubmed/23576039

摘要

背景：

朝鮮薊通常作為蔬菜食用；其葉子通常用於民間醫學中對肝炎、高脂血症、肥胖和消化不良病症的治療。本研究的目的是確定朝鮮薊花苞鱗苞片的酒精萃取物的揮發油和化學成分。另外，甲醇提取物作為對大鼠乙醇誘發的胃潰瘍的抗潰瘍劑的作用進行了評價。

結果：

從甲醇中萃取制得六種類黃酮和一種酚酸。此外，被鑑定出37種的揮發油，大部分包括單萜和倍半萜。口服朝鮮薊提取物（200和400mg千克-1）顯著地（P <0.05）降低了胃潰瘍指數（55.33％和72.14％的抑制率）。大鼠胃的病理組織學檢查表明，朝鮮薊誘導增加胃粘液生產，並減少了深度的嚴重性粘膜病變。

朝鮮薊劑量依賴性降低了酒精胃升高的丙二醛(MDA)，和降低穀胱甘肽水平和過氧化氫酶的活性。這些結果表明，朝鮮薊的花苞鱗苞片具有潛在的抗潰瘍活性。

結論：

本論文首度描述介紹了甲醇萃取物揮發油的鑑定、分離和成分鑑定。此外，同將首次在這建立了朝鮮薊花苞鱗苞片在高防潰瘍的潛力。

 Ç2013化工協會

Herb: Artichoke, original Author Maria-Teresa Marti

Herb: Artichoke, original Author Maria-Teresa Marti
Herb: Artichoke, original Author Maria-Teresa Marti

http://www.ucdenver.edu/academics/colleges/pharmacy/currentstudents/OnCampusPharmDStudents/ExperientialProgram/Documents/nutr_monographs/Monograph-artichoke.pdf

Health Benefits of Globe Artichokes

Health Benefits of Globe Artichokes朝鮮薊的健康益處

http://www.rjmazza.net.au/index_htm_files/Health%20Benefits.pdf    

Artichokes

Artichokes朝鮮薊
Artichokes朝鮮薊

The Health Benefits of Artichokes, by Dr Wayne Terai

The Health Benefits of Artichokes 朝鮮薊對健康的益處
http://www.burtchchiropractic.com/media/1001_ArtichokesHealthBenefits.pdf

The Health Benefits of Artichokes朝鮮薊對健康的益處

2008 Effect of pretreatment with artichoke extract on carbon tetrachloride-induced liver injury and oxidative stress以朝鮮薊萃取物預處理對四氯化碳誘導的肝損傷和氧化應激之效果

·        2008 Güldal Mehmetçik el., Effect of pretreatment with artichoke extract on carbon tetrachloride-induced liver injury and oxidative stress, Volume 60, Issue 6, 18 September 2008, Pages 475–480, Experimental and Toxicologic Pathology (IF: 2.144)

·          2008 以朝鮮薊萃取物預處理對四氯化碳誘導的肝損傷和氧化應激之效果

研究結果表明，在體內以朝鮮薊萃取物給藥可用於對四氯化碳誘導的肝損傷和肝毒性，在預防氧化應激的很有用的。

【說明：以四氯化碳模擬大鼠肝功能所受之化學毒害，而服用朝鮮薊可顯示具有很強大的保護肝臟的作用。】

Artichoke is a plant with antioxidant properties. In this study, we investigated the effect of artichoke extract pretreatment on carbon tetrachloride (CCl₄)-induced oxidative stress and hepatotoxicity. Rats were given artichoke leaf extract (1.5 g/kg/day) by gavage for 2 weeks and after then CCl₄ (1 ml/kg; i.p.) was applied. All rats were killed 24 h after the CCl₄ injection. CCl₄ administration resulted in hepatic necrosis and significant increases in plasma transaminase activities as well as hepatic malondialdehyde (MDA) and diene conjugate (DC) levels in the liver of rats. Glutathione (GSH) and vitamin C levels decreased, but vitamin E levels increased in the liver of CCl₄-treated rats. Hepatic superoxide dismutase (SOD) activities remained unchanged, but glutathione peroxidase (GSH-Px) and glutathione transferase (GST) activities decreased following CCl₄ treatment. In rats pretreated with artichoke extract, significant decreases in plasma transaminase activities and amelioration in histopathological changes in the liver were observed following CCl₄ treatment as compared to CCl₄-treated rats. In addition, hepatic MDA and DC levels decreased, but GSH levels and GSH-Px activities increased without any change in other antioxidant parameters following CCl₄ treatment in artichoke-pretreated rats. The present findings indicate that in vivoarchitoke extract administration may be useful for the prevention of oxidative stress-induced hepatotoxicity.

朝鮮薊是具有抗氧化性質的植物。在這項研究中，我們調查以朝鮮薊提取物預處理對四氯化碳(CCl ₄ ) 誘導的氧化應激和肝毒性的影響。大鼠通過強飼法給予朝鮮薊葉提取物（1.5克/千克/天）2週，在此之後使用注射CCl ₄（1毫升/公斤; IP）。所有大鼠在注入四氯化碳24小時後犧牲。CCl ₄給藥在大鼠的肝臟導致肝壞死和顯著增加血漿轉氨酶(transaminase)的活性以及肝丙二醛（MDA, malondialdehyde）和共軛二烯（DC, diene conjugate）的水平。還原型穀胱甘肽（GSH, Glutathione）和維生素C含量減少，但維生素E含量在CCl ₄處理過的大鼠肝臟有增加。肝超氧化歧化酶（SOD, superoxide dismutase）的活性保持不變，但穀胱甘肽過氧化酶（GSH-PX, glutathione peroxidase）和穀胱甘肽轉移酶（GST, glutathione transferase）活性降低隨著四氯化碳的處理。在大鼠中以朝鮮薊提取物預處理(餵食)，在肝組織病​​理觀察到在相比於四氯化碳處理過的大鼠的變化，血漿中的轉氨酶活性顯著下跌和改善。此外，肝的MDA和DC的水平有所下降，但GSH含量和GSH-Px活性增加，而在其他抗氧化參數沒有任何變化隨著四氯化碳注射在朝鮮薊預處理的大鼠上。本研究結果表明，在體內 Artichoke朝鮮薊提取物給藥可用於預防氧化應激誘導的肝毒性的很有用的。