2008 Artichoke Leaf Extract Lowers Cholesterol
Researchers
have found that an over-the-counter Artichoke Leaf Extract (ALE) from the globe
artichoke plant can lower cholesterol in otherwise healthy individuals with
moderately raised levels. Cardiovascular diseases are the chief causes of death
in the UK, and are associated with raised circulating levels of total
cholesterol in the plasma.
Once plasma cholesterol reaches a certain
level, drugs such as statins are often prescribed to help reduce it.
Intervention before concentrations reaches these levels may help reduce the
risk of developing cardiovascular diseases without the need for drugs. This new piece of research has shown that otherwise healthy
people with moderately raised plasma cholesterol may be able to lower their
levels by taking this herbal supplement.
During the trial, 75 volunteers were given 1280mg (4 capsules)
of an ALE, or matched placebo, each day for 12 weeks. ALE consumption resulted
in a modest but favourable statistically significant reduction in total plasma
cholesterol after the intervention period.
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朝鮮薊葉萃取物降低膽固醇
研究人員發現，從朝鮮薊植物萃取的非醫師處方朝鮮薊葉萃取物（ALE）可以用於健康人體的適度減緩與降低膽固醇水平。在英國心血管疾病是導致死亡的要成因，並與血漿中總膽固醇增加具循環水平相關聯。
一旦血漿膽固醇達到一定程度，往往建議處方使用如他汀類(Statins)藥物以協助降低它。達到這些濃度水平前而不需要使用藥物的風險，介入治療可能有助於降低罹患心血管疾病。這項新的研究已經表明原本健康的人有溫和升高血漿膽固醇的趨勢，可以通過服用這種草藥作補充劑，以降低他們血漿膽固醇的水平。
在試驗中，75名志願者每一天給予的朝鮮薊萃取物(ALE)1,280mg（4粒），或12週相對應的安慰劑。在期間後ALE的使用者產生在統計學優良顯著降低血漿總膽固醇的溫和效果。
【注意：內容以原文為主，譯文僅供參考，有興趣請到原網址查閱與深入了解/CL/】
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Journal Reference:
Bundy R., et al. Artichoke
leaf extract (Cynara scolymus) reduces plasma cholesterol in otherwise healthy
hypercholesterolemic adults: a randomised double-blind placebo controlled trial. Phytomedicine, DOI:10.1016/j.phymed.2008.03.001
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